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Noncompetitive Enzyme Inhibition

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A non-substrate molecule binds to an enzyme at a location other than the active site, rendering the enzyme unable to bind its substrate. Which of the following has most likely occurred?
A

An activator has bound to the substrate.

B

The reaction has been catalyzed.

C

A competitive inhibitor has bound to the enzyme.

D

The active site has undergone a conformational change.

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